In attempting to run more like a barefoot runner (currently up to 1.5 miles by the way - its going well) I have stopped wearing socks when I run in trainers.
Socks change the shape of your foot. specifically they make your toes bunch up when ideally they should splay out as you touch down.
I noticed this particularly when I bought a pack of very cheap socks from JJB sports a few weeks back - they say 9 -11 but, as a size 11, I found them very tight. This made that feeling of not having enough room at the front of my shoe very pronounced. So I took em off.
Apart from a small blister the first time out I've had no problems. My shoes feel roomier and I feel like I am striking the ground (and springing off) more naturally.
I don't suppose this will do much for the wonderful bouquet my trainers give off but you can't have everything.